Iron, inflammation and invasion of cancer cells.
Ontology highlight
ABSTRACT:
SUBMITTER: Fischer-Fodor E
PROVIDER: S-EPMC4632882 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Iron, inflammation and invasion of cancer cells.
Fischer-Fodor Eva E Miklasova Natalia N Berindan-Neagoe Ioana I Saha Bhaskar B
Clujul medical (1957) 20150701 3
Chronic inflammation is associated with the metastasis of tumor cells evolving from a benign tumor to disseminating cancer. Such a metastatic progression is fostered by the angiogenesis propelled by various mediators interacting at the site of tumor growth. Angiogenesis causes two major changes that are assisted by altered glycosylation and neo-antigen presentation by the cancer cells. The angiogenesis-promoted pathological changes include enhanced inflammation and degradation of tissue matrices ...[more]
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