Ontology highlight
ABSTRACT:
SUBMITTER: Alazami AM
PROVIDER: S-EPMC4634911 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Alazami Anas M AM Awad Salma M SM Coskun Serdar S Al-Hassan Saad S Hijazi Hadia H Abdulwahab Firdous M FM Poizat Coralie C Alkuraya Fowzan S FS
Genome biology 20151105
<h4>Background</h4>Embryonic lethality is a recognized phenotypic expression of individual gene mutations in model organisms. However, identifying embryonic lethal genes in humans is challenging, especially when the phenotype is manifested at the preimplantation stage.<h4>Results</h4>In an ongoing effort to exploit the highly consanguineous nature of the Saudi population to catalog recessively acting embryonic lethal genes in humans, we have identified two families with a female-limited infertil ...[more]