Ontology highlight
ABSTRACT:
SUBMITTER: Maton G
PROVIDER: S-EPMC4636119 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Maton Gilliane G Edwards Frances F Lacroix Benjamin B Stefanutti Marine M Laband Kimberley K Lieury Tiffany T Kim Taekyung T Espeut Julien J Canman Julie C JC Dumont Julien J
Nature cell biology 20150413 5
A critical structure poised to coordinate chromosome segregation with division plane specification is the central spindle that forms between separating chromosomes after anaphase onset. The central spindle acts as a signalling centre that concentrates proteins essential for division plane specification and contractile ring constriction. However, the molecular mechanisms that control the initial stages of central spindle assembly remain elusive. Using Caenorhabditis elegans zygotes, we found that ...[more]