Impact of a Contralateral Tumor Nodule on Survival in Non-Small-Cell Lung Cancer.

ABSTRACT:

Introduction

Contralateral lung tumors in non-small-cell lung cancer (NSCLC) are classified as stage M1a yet may represent hematogenous metastases or synchronous primary tumors. The impact of these tumors on overall survival (OS) is poorly understood. Here, we aim to determine whether NSCLC patients with M1a disease due only to a contralateral tumor nodule exhibit a favorable prognosis relative to other M1a or M1b patients.

Methods

Retrospective evaluation of the impact of contralateral tumor nodules on OS in NSCLC stratified by primary tumor size and N stage attained from Surveillance, Epidemiology, and End Results database.

Results

Of 173,640 patients, 5161 M1a-contra patients were identified. Median and 3-year OS for these patients exceeded that of patients with M1

SUBMITTER: Morris ZS 

PROVIDER: S-EPMC4636460 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature