Ontology highlight
ABSTRACT:
SUBMITTER: Weinstock M
PROVIDER: S-EPMC4647139 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Weinstock Matthew M McDermott David D
Therapeutic advances in urology 20151201 6
Immunostimulatory therapies have been a cornerstone of treatment for metastatic renal cell carcinoma (RCC) since the 1990s. However, the use of traditional immunotherapeutic approaches for RCC, such as high-dose interleukin-2 and interferon-α, has been limited by significant systemic toxicities and the need to deliver these therapies at centers of expertise. Furthermore, in spite of the success of these immunostimulatory therapies for some patients with RCC, it is clear that most patients fail t ...[more]