Ontology highlight
ABSTRACT:
SUBMITTER: Guan G
PROVIDER: S-EPMC4648274 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Guan Guohua G Pinochet-Barros Azul A Gaballa Ahmed A Patel Sarju J SJ Argüello José M JM Helmann John D JD
Molecular microbiology 20150910 4
Iron is an essential element for nearly all cells and limited iron availability often restricts growth. However, excess iron can also be deleterious, particularly when cells expressing high affinity iron uptake systems transition to iron rich environments. Bacillus subtilis expresses numerous iron importers, but iron efflux has not been reported. Here, we describe the B. subtilis PfeT protein (formerly YkvW/ZosA) as a P1B4 -type ATPase in the PerR regulon that serves as an Fe(II) efflux pump and ...[more]