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Norovirus Antigen Detection with a Combination of Monoclonal and Single-Chain Antibodies.

ABSTRACT: The performance of a norovirus antigen detection assay was assessed using monoclonal antibody NV23 and single-chain antibody HJT-R3-A9 to identify both virus-like particles and virus-containing fecal samples. The detection of 25 different norovirus genotypes as recombinant virus-like particles or in clinical samples was dependent on virus or antigen concentration.

SUBMITTER: Kou B

PROVIDER: S-EPMC4652105 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Norovirus Antigen Detection with a Combination of Monoclonal and Single-Chain Antibodies.

Kou Baijun B Huang Wanzhi W Neill Frederick H FH Palzkill Timothy T Estes Mary K MK Atmar Robert L RL

Journal of clinical microbiology 20151007 12

The performance of a norovirus antigen detection assay was assessed using monoclonal antibody NV23 and single-chain antibody HJT-R3-A9 to identify both virus-like particles and virus-containing fecal samples. The detection of 25 different norovirus genotypes as recombinant virus-like particles or in clinical samples was dependent on virus or antigen concentration. ...[more]

PMID: 26447115

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