Ontology highlight
ABSTRACT:
SUBMITTER: Hosomichi K
PROVIDER: S-EPMC4660052 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Hosomichi Kazuyoshi K Shiina Takashi T Tajima Atsushi A Inoue Ituro I
Journal of human genetics 20150827 11
In the past decade, the development of next-generation sequencing (NGS) has paved the way for whole-genome analysis in individuals. Research on the human leukocyte antigen (HLA), an extensively studied molecule involved in immunity, has benefitted from NGS technologies. The HLA region, a 3.6-Mb segment of the human genome at 6p21, has been associated with more than 100 different diseases, primarily autoimmune diseases. Recently, the HLA region has received much attention because severe adverse e ...[more]