Ontology highlight
ABSTRACT:
SUBMITTER: Mesentier-Louro LA
PROVIDER: S-EPMC4663341 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Stem cells international 20151116
Following optic nerve injury associated with acute or progressive diseases, retinal ganglion cells (RGCs) of adult mammals degenerate and undergo apoptosis. These diseases have limited therapeutic options, due to the low inherent capacity of RGCs to regenerate and due to the inhibitory milieu of the central nervous system. Among the numerous treatment approaches investigated to stimulate neuronal survival and axonal extension, cell transplantation emerges as a promising option. This review focus ...[more]