Ontology highlight
ABSTRACT:
SUBMITTER: Ogaki S
PROVIDER: S-EPMC4663490 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Ogaki Soichiro S Morooka Mayu M Otera Kaito K Kume Shoen S
Scientific reports 20151130
The human intestinal epithelium is a useful model for pharmacological studies of absorption, metabolism, drug interactions, and toxicology, as well as for studies of developmental biology. We established a rapid and cost effective system for differentiation of human induced pluripotent stem (iPS) cells into definitive endoderm (DE) cells. In the presence of dimethyl sulfoxide (DMSO), a low concentration of Activin at 6.25 ng/ml is sufficient to give a similar differentiation efficiency with that ...[more]