Ontology highlight
ABSTRACT:
SUBMITTER: Fang L
PROVIDER: S-EPMC4667703 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Fang Lishan L Cai Junchao J Chen Baixue B Wu Shanshan S Li Rong R Xu Xiaonan X Yang Yi Y Guan Hongyu H Zhu Xun X Zhang Le L Yuan Jie J Wu Jueheng J Li Mengfeng M
Nature communications 20151015
Cancer stem cells (CSCs) are involved in tumorigenesis, tumour recurrence and therapy resistance and Wnt signalling is essential for the development of the biological traits of CSCs. In non-small cell lung carcinoma (NSCLC), unlike in colon cancer, mutations in β-catenin and APC genes are uncommon; thus, the mechanism underlying the constitutive activation of Wnt signalling in NSCLC remains unclear. Here we report that miR-582-3p expression correlates with the overall- and recurrence-free-surviv ...[more]