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Electronic communication of cells with a surface mediated by boronic acid saccharide interactions.

ABSTRACT: The fabrication of a molecularly tailored surface functionalised with a saccharide binding motif, a phenyl boronic acid derivative is reported. The functionalised surface facilitated the transfer of electrons, via unique electronic interactions mediated by the presence of the boronic acid, from a macrophage cell line. This is the first example of eukaryotic cellular-electrical communication mediated by the binding of cells via their cell-surface saccharide units.

SUBMITTER: Stephenson-Brown A

PROVIDER: S-EPMC4668958 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Electronic communication of cells with a surface mediated by boronic acid saccharide interactions.

Stephenson-Brown Alex A Yong Sue S Mansor Muhammad H MH Hussein Zarrar Z Yip Nga-Chi NC Mendes Paula M PM Fossey John S JS Rawson Frankie J FJ

Chemical communications (Cambridge, England) 20151201 97

The fabrication of a molecularly tailored surface functionalised with a saccharide binding motif, a phenyl boronic acid derivative is reported. The functionalised surface facilitated the transfer of electrons, via unique electronic interactions mediated by the presence of the boronic acid, from a macrophage cell line. This is the first example of eukaryotic cellular-electrical communication mediated by the binding of cells via their cell-surface saccharide units. ...[more]

PMID: 26413585

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