Ontology highlight
ABSTRACT:
SUBMITTER: Grinias JP
PROVIDER: S-EPMC4669065 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Grinias James P JP Kennedy Robert T RT
Chromatography (Basel) 20150804 3
Large-size (4-5 µm) superficially porous particles yield lower plate heights (e.g., the minimal reduced plate height or <i>h<sub>min</sub></i> ≈ 1.5) than fully porous particles of a similar size when packed into large-bore columns. This property allows for better chromatographic performance without the higher pressures required for smaller particles. This study explores the use of such particles in microfluidic LC columns where materials and fitting pressure limits can constrain the size of par ...[more]