Ontology highlight
ABSTRACT:
SUBMITTER: Hori A
PROVIDER: S-EPMC4669408 | biostudies-literature | 2015 Dec 4-11
REPOSITORIES: biostudies-literature
Hori Akiko A Morand Agathe A Ikebe Chiho C Frith David D Snijders Ambrosius P AP Toda Takashi T
Biochemical and biophysical research communications 20151110 1-2
The centrosome plays a pivotal role in a wide range of cellular processes and its dysfunction is causally linked to many human diseases including cancer and developmental and neurological disorders. This organelle contains more than one hundred components, and yet many of them remain uncharacterised. Here we identified a novel centrosome protein Wdr8, based upon the structural conservation of the fission yeast counterpart. We showed that Wdr8 constitutively localises to the centrosome and super ...[more]