How to Improve the Survival of Transplanted Mesenchymal Stem Cell in Ischemic Heart?
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SUBMITTER: Li L
PROVIDER: S-EPMC4670674 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
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How to Improve the Survival of Transplanted Mesenchymal Stem Cell in Ischemic Heart?
Li Liangpeng L Chen Xiongwen X Wang Wei Eric WE Zeng Chunyu C
Stem cells international 20151122
Mesenchymal stem cell (MSC) is an intensely studied stem cell type applied for cardiac repair. For decades, the preclinical researches on animal model and clinical trials have suggested that MSC transplantation exerts therapeutic effect on ischemic heart disease. However, there remain major limitations to be overcome, one of which is the very low survival rate after transplantation in heart tissue. Various strategies have been tried to improve the MSC survival, and many of them showed promising ...[more]
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