Infectious Progeny of 2009 A (H1N1) Influenza Virus Replicated in and Released from Human Neutrophils.
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ABSTRACT:
SUBMITTER: Zhang Z
PROVIDER: S-EPMC4671072 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
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Infectious Progeny of 2009 A (H1N1) Influenza Virus Replicated in and Released from Human Neutrophils.
Zhang Zhang Z Huang Tao T Yu Feiyuan F Liu Xingmu X Zhao Conghui C Chen Xueling X Kelvin David J DJ Gu Jiang J
Scientific reports 20151207
Various reports have indicated that a number of viruses could infect neutrophils, but the multiplication of viruses in neutrophils was abortive. Based on our previous finding that avian influenza viral RNA and proteins were present in the nucleus of infected human neutrophils in vivo, we investigated the possibility of 2009 A (H1N1) influenza viral synthesis in infected neutrophils and possible release of infectious progeny from host cells. In this study we found that human neutrophils in vitro ...[more]
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