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Scalable lithography from Natural DNA Patterns via polyacrylamide gel.

ABSTRACT: A facile strategy for fabricating scalable stamps has been developed using cross-linked polyacrylamide gel (PAMG) that controllably and precisely shrinks and swells with water content. Aligned patterns of natural DNA molecules were prepared by evaporative self-assembly on a PMMA substrate, and were transferred to unsaturated polyester resin (UPR) to form a negative replica. The negative was used to pattern the linear structures onto the surface of water-swollen PAMG, and the pattern sizes on the PAMG stamp were customized by adjusting the water content of the PAMG. As a result, consistent reproduction of DNA patterns could be achieved with feature sizes that can be controlled over the range of 40%-200% of the original pattern dimensions. This methodology is novel and may pave a new avenue for manufacturing stamp-based functional nanostructures in a simple and cost-effective manner on a large scale.

SUBMITTER: Qu J

PROVIDER: S-EPMC4671135 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Scalable lithography from Natural DNA Patterns via polyacrylamide gel.

Qu JieHao J Hou XianLiang X Fan WanChao W Xi GuangHui G Diao HongYan H Liu XiangDon X

Scientific reports 20151207

A facile strategy for fabricating scalable stamps has been developed using cross-linked polyacrylamide gel (PAMG) that controllably and precisely shrinks and swells with water content. Aligned patterns of natural DNA molecules were prepared by evaporative self-assembly on a PMMA substrate, and were transferred to unsaturated polyester resin (UPR) to form a negative replica. The negative was used to pattern the linear structures onto the surface of water-swollen PAMG, and the pattern sizes on the ...[more]

PMID: 26639572

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