Ontology highlight
ABSTRACT:
SUBMITTER: Castello A
PROVIDER: S-EPMC4671484 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Castello Alfredo A Hentze Matthias W MW Preiss Thomas T
Trends in endocrinology and metabolism: TEM 20151028 12
In the past century, few areas of biology advanced as much as our understanding of the pathways of intermediary metabolism. Initially considered unimportant in terms of gene regulation, crucial cellular fate changes, cell differentiation, or malignant transformation are now known to involve 'metabolic remodeling' with profound changes in the expression of many metabolic enzyme genes. This review focuses on the recent identification of RNA-binding activity of numerous metabolic enzymes. We discus ...[more]