Ontology highlight
ABSTRACT:
SUBMITTER: Solari C
PROVIDER: S-EPMC4671669 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Solari Claudia C Vázquez Echegaray Camila C Cosentino María Soledad MS Petrone María Victoria MV Waisman Ariel A Luzzani Carlos C Francia Marcos M Villodre Emilly E Lenz Guido G Miriuka Santiago S Barañao Lino L Guberman Alejandra A
PloS one 20151207 12
Pluripotent stem cells possess complex systems that protect them from oxidative stress and ensure genomic stability, vital for their role in development. Even though it has been reported that antioxidant activity diminishes along stem cell differentiation, little is known about the transcriptional regulation of the involved genes. The reported modulation of some of these genes led us to hypothesize that some of them could be regulated by the transcription factors critical for self-renewal and pl ...[more]