Ontology highlight
ABSTRACT:
SUBMITTER: Migita K
PROVIDER: S-EPMC4677039 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Migita Kiyoshi K Jiuchi Yuka Y Furukawa Hiroshi H Nakamura Minoru M Komori Atsumasa A Yasunami Michio M Kozuru Hideko H Abiru Seigo S Yamasaki Kazumi K Nagaoka Shinya S Hashimoto Satoru S Bekki Shigemune S Yoshizawa Kaname K Shimada Masaaki M Kouno Hiroshi H Kamitsukasa Hiroshi H Komatsu Tatsuji T Hijioka Taizo T Nakamuta Makoto M Naganuma Atsushi A Yamashita Haruhiro H Nishimura Hideo H Ohta Hajime H Nakamura Yoko Y Ario Keisuke K Oohara Yukio Y Sugi Kazuhiro K Tomizawa Minoru M Sato Takeaki T Takahashi Hironao H Muro Toyokichi T Makita Fujio F Mita Eiji E Sakai Hironori H Yatsuhashi Hiroshi H
BMC research notes 20151212
<h4>Background</h4>Previous genome-wide association studies have evaluated the impact of common genetic variants and identified several non-HLA risk loci associated with autoimmune liver diseases. More recent genome-wide association studies and replication analyses reported an association between variants of the CARD10 polymorphism rs6000782 and risk of type 1 autoimmune hepatitis (AIH). In this case-control study, we genotyped 326 Japanese AIH patients and 214 control subjects.<h4>Results</h4>G ...[more]