Lack of association between IL10 polymorphisms and sarcoidosis in Japanese patients.
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ABSTRACT:
SUBMITTER: Sakuyama K
PROVIDER: S-EPMC3291520 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Publications
Lack of association between IL10 polymorphisms and sarcoidosis in Japanese patients.
Sakuyama Kenichi K Meguro Akira A Ota Masao M Ishihara Mami M Uemoto Riyo R Ito Haruyasu H Okada Eiichi E Namba Kenichi K Kitaichi Nobuyoshi N Morimoto Shin-ichiro S Kaburaki Toshikatsu T Ando Yasutaka Y Takenaka Shinobu S Yuasa Takenosuke T Ohno Shigeaki S Inoko Hidetoshi H Mizuki Nobuhisa N
Molecular vision 20120125
<h4>Purpose</h4>To investigate whether interleukin 10 (IL10) gene polymorphisms are associated with the development of sarcoidosis in Japanese patients.<h4>Methods</h4>Two hundred and eighty-eight Japanese sarcoidosis patients and 310 Japanese healthy controls were recruited. We genotyped 9 single-nucleotide polymorphisms in IL10 and assessed the allelic diversity between cases and controls.<h4>Results</h4>No significant differences in the frequency of IL10 alleles, genotypes, and haplotypes in ...[more]
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