A Perspective on the Role of microRNA-128 Regulation in Mental and Behavioral Disorders.
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ABSTRACT:
SUBMITTER: Ching AS
PROVIDER: S-EPMC4677093 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
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A Perspective on the Role of microRNA-128 Regulation in Mental and Behavioral Disorders.
Ching Ai-Sze AS Ahmad-Annuar Azlina A
Frontiers in cellular neuroscience 20151214
MiRNAs are short, non-coding RNA molecules that regulate gene expression post-transcriptionally. Over the past decade, misregulated miRNA pathways have been associated with various diseases such as cancer, neurodegenerative diseases, and neurodevelopmental disorders. In this article, we aim to discuss the role played by miR-128 in neuropsychiatric disorders, and highlight potential target genes from an in silico analysis of predicted miR-128 targets. We also discuss the differences of target gen ...[more]
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