Ontology highlight
ABSTRACT:
SUBMITTER: Markandona O
PROVIDER: S-EPMC4681734 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Markandona Ourania O Dafopoulos Konstantinos K Anifandis George G Messini Christina I CI Dimitraki Marina M Tsezou Aspasia A Georgoulias Panagiotis P Messinis Ioannis E IE
Journal of assisted reproduction and genetics 20151031 12
<h4>Purpose</h4>MLH3, a MutL homolog protein in mammals playing a role in DNA mismatch repair, is associated with spermatogenesis and male infertility. The purpose of the present study was to investigate the association of the single-nucleotide polymorphism (SNP), rs 175080 in the MLH3 gene, with sperm parameters in a Greek population.<h4>Methods</h4>The study included 300 men of couples undergoing in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) treatments ( ...[more]