Ontology highlight
ABSTRACT:
SUBMITTER: Agarwal P
PROVIDER: S-EPMC4694582 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20150731 39
Vertebrate glycans constitute a large, important, and dynamic set of post-translational modifications that are notoriously difficult to manipulate and image. Although the chemical reporter strategy has been used in conjunction with bioorthogonal chemistry to image the external glycosylation state of live zebrafish and detect tumor-associated glycans in mice, the ability to image glycans systemically within a live organism has remained elusive. Here, we report a method that combines the metabolic ...[more]