Ontology highlight
ABSTRACT:
SUBMITTER: Xu D
PROVIDER: S-EPMC4694719 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Xu Dongqing D Lin Fang F Jiang Yan Y Ling Junjie J Hettiarachchi Chamari C Tellgren-Roth Christian C Holm Magnus M Wei Ning N Deng Xing Wang XW
PLoS genetics 20151229 12
CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1) functions as an E3 ubiquitin ligase and mediates a variety of developmental processes in Arabidopsis by targeting a number of key regulators for ubiquitination and degradation. Here, we identify a novel COP1 interacting protein, COP1 SUPPRESSOR 2 (CSU2). Loss of function mutations in CSU2 suppress the constitutive photomorphogenic phenotype of cop1-6 in darkness. CSU2 directly interacts with COP1 via their coiled-coil domains and is recruited by COP1 into n ...[more]