Semi-permeable Diffusion Barriers Enhance Patterning Robustness in the C. elegans Germline.
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ABSTRACT:
SUBMITTER: Cinquin A
PROVIDER: S-EPMC4694723 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Publications
Semi-permeable Diffusion Barriers Enhance Patterning Robustness in the C. elegans Germline.
Cinquin Amanda A Zheng Likun L Taylor Pete H PH Paz Adrian A Zhang Lei L Chiang Michael M Snow Joshua J JJ Nie Qing Q Cinquin Olivier O
Developmental cell 20151101 4
Positional information derived from local morphogen concentration plays an important role in patterning. A key question is how morphogen diffusion and gene expression regulation shape positional information into an appropriate profile with suitably low noise. We address this question using a model system--the C. elegans germline--whose regulatory network has been well characterized genetically but whose spatiotemporal dynamics are poorly understood. We show that diffusion within the germline syn ...[more]
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