Ontology highlight
ABSTRACT:
SUBMITTER: Hugen N
PROVIDER: S-EPMC4694861 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
Hugen Niek N Simmer Femke F Mekenkamp Leonie J M LJ Koopman Miriam M van den Broek Evert E de Wilt Johannes H W JH Punt Cornelis J A CJ Ylstra Bauke B Meijer Gerrit A GA Nagtegaal Iris D ID
Oncotarget 20150901 28
<h4>Background</h4>Mucinous carcinoma (MC) is found in 10%-15% of colorectal cancer (CRC) patients. It differs from the common adenocarcinoma (AC) in histopathological appearance and clinical behavior.<h4>Methods</h4>Genome-wide DNA copy number and survival data from MC and AC primary CRC samples from patients from two phase III trials (CAIRO and CAIRO2) was compared. Chromosomal copy number data from The Cancer Genome Atlas (TCGA) was used for validation. Altogether, 470 ACs were compared to 57 ...[more]