Ontology highlight
ABSTRACT:
SUBMITTER: Patel DJ
PROVIDER: S-EPMC4696766 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Patel Dinshaw J DJ Wang Zhanxin Z
Annual review of biochemistry 20130101
This review focuses on a structure-based analysis of histone posttranslational modification (PTM) readout, where the PTMs serve as docking sites for reader modules as part of larger complexes displaying chromatin modifier and remodeling activities, with the capacity to alter chromatin architecture and templated processes. Individual topics addressed include the diversity of reader-binding pocket architectures and common principles underlying readout of methyl-lysine and methyl-arginine marks, th ...[more]