Ontology highlight
ABSTRACT:
SUBMITTER: Liu YF
PROVIDER: S-EPMC4699370 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Liu Ya-Fen YF Tsai Pei-Yun PY Lin Fong-Yuan FY Lin Kuan-Hsun KH Chang Tien-Jye TJ Lin Hui-Wen HW Chulakasian Songkhla S Hsu Wei-Li WL
Veterinary research 20151224
Pseudorabies virus (PrV) belongs to the α-herpesvirinae of which human simplex virus (HSV) is the prototype virus. One of the hallmarks of HSV infection is shutoff of protein synthesis that is mediated by various viral proteins including vhs (virion host shutoff), which is encoded by the UL41 gene. However, the function of PrV vhs is poorly understood. Due to the low sequence similarity (39.3%) between the HSV and PrV UL41 proteins, vhs might not share the same biochemistry characteristics. The ...[more]