Intranasal inoculation of sows with highly pathogenic porcine reproductive and respiratory syndrome virus at mid-gestation causes transplacental infection of fetuses.
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ABSTRACT:
SUBMITTER: Wang T
PROVIDER: S-EPMC4699371 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
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Intranasal inoculation of sows with highly pathogenic porcine reproductive and respiratory syndrome virus at mid-gestation causes transplacental infection of fetuses.
Wang Tongtong T Wang Xiaofei X Li Xin-An XA Nie Li L Zhang Minxia M Liu Sidang S Zhao Xiaomin X Shang Yingli Y Zhou En-Min EM Hiscox Julian A JA Xiao Yihong Y
Veterinary research 20151229
Transplacental infection plays a critical role in the reproductive failure induced by porcine reproductive and respiratory syndrome virus (PRRSV), yet exposure of sows and gilts to classical PRRSV generally leads to reproductive failure after 85 days of gestation. We report, for the first time, that the susceptibility of fetuses to highly pathogenic PRRSV (HP-PRRSV) is similar at 60 days and 90 days of gestation. This difference from classical PRRSV may contribute to its high pathogenicity. A fi ...[more]
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