Ontology highlight
ABSTRACT:
SUBMITTER: Pichugina T
PROVIDER: S-EPMC4700429 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Pichugina T T Sugawara T T Kaykov A A Schierding W W Masuda K K Uewaki J J Grand R S RS Allison J R JR Martienssen R A RA Nurse P P Ueno M M O'Sullivan J M JM
Scientific reports 20160105
The locations of proteins and epigenetic marks on the chromosomal DNA sequence are believed to demarcate the eukaryotic genome into distinct structural and functional domains that contribute to gene regulation and genome organization. However, how these proteins and epigenetic marks are organized in three dimensions remains unknown. Recent advances in proximity-ligation methodologies and high resolution microscopy have begun to expand our understanding of these spatial relationships. Here we use ...[more]