Ontology highlight
ABSTRACT:
SUBMITTER: Alves JM
PROVIDER: S-EPMC4700947 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Genome biology and evolution 20151111 12
A polymorphic inversion that lies on chromosome 17q21 comprises two major haplotype families (H1 and H2) that not only differ in orientation but also in copy-number. Although the processes driving the spread of the inversion-associated lineage (H2) in humans remain unclear, a selective advantage has been proposed for one of its subtypes. Here, we genotyped a large panel of individuals from previously overlooked populations using a custom array with a unique panel of H2-specific single nucleotide ...[more]