Ontology highlight
ABSTRACT:
SUBMITTER: Hagen C
PROVIDER: S-EPMC4701712 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Hagen Christoph C Dent Kyle C KC Zeev-Ben-Mordehai Tzviya T Grange Michael M Bosse Jens B JB Whittle Cathy C Klupp Barbara G BG Siebert C Alistair CA Vasishtan Daven D Bäuerlein Felix J B FJ Cheleski Juliana J Werner Stephan S Guttmann Peter P Rehbein Stefan S Henzler Katja K Demmerle Justin J Adler Barbara B Koszinowski Ulrich U Schermelleh Lothar L Schneider Gerd G Enquist Lynn W LW Plitzko Jürgen M JM Mettenleiter Thomas C TC Grünewald Kay K
Cell 20151201 7
Vesicular nucleo-cytoplasmic transport is becoming recognized as a general cellular mechanism for translocation of large cargoes across the nuclear envelope. Cargo is recruited, enveloped at the inner nuclear membrane (INM), and delivered by membrane fusion at the outer nuclear membrane. To understand the structural underpinning for this trafficking, we investigated nuclear egress of progeny herpesvirus capsids where capsid envelopment is mediated by two viral proteins, forming the nuclear egres ...[more]