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Rhodamine analogues for molecular ruler applications.


ABSTRACT: A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally.

SUBMITTER: Chu YH 

PROVIDER: S-EPMC4702047 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature

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Rhodamine analogues for molecular ruler applications.

Chu Yu-Hsuan YH   Escobedo Jorge O JO   Jiang Meiyan M   Steyger Peter S PS   Strongin Robert M RM  

Dyes and pigments : an international journal 20160301


A series of geometrically well-defined cationic fluorophores were designed based on molecular mechanics. They contain biaryl linkers to impart rigidity preventing intramolecular folding between a conjugated biomolecule and fluorophore. All probes have absorption and emission maxima within 20 nm from Texas Red, as predicted by TDDFT calculations and validated experimentally. ...[more]

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