Ontology highlight
ABSTRACT:
SUBMITTER: Guo JJ
PROVIDER: S-EPMC4703515 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Guo Jason J JJ Yang De-Ping DP Tian Xiaoyu X Vemuri V Kiran VK Yin Dali D Li Chen C Duclos Richard I RI Shen Lingling L Ma Xiaoyu X Janero David R DR Makriyannis Alexandros A
Biochimica et biophysica acta 20151201 2
Non-genomic membrane effects of estrogens are of great interest because of the diverse biological activities they may elicit. To further our understanding of the molecular features of the interaction between estrogenic hormones and membrane bilayers, we have determined the preferred orientation, location, and dynamic properties of 17β-estradiol (E2) in two different phospholipid membrane environments using (2)H-NMR and 2D (1)H-(13)C HSQC in conjunction with molecular dynamics simulations. Unequi ...[more]