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Cell and Protein Recognition at a Supported Bilayer Interface via In Situ Cavitand-Mediated Functional Polymer Growth.

ABSTRACT: Water-soluble deep cavitands embedded in a supported lipid bilayer are capable of anchoring ATRP initiator molecules for the in situ synthesis of primary amine-containing polymethacrylate patches at the water:membrane interface. These polymers can be derivatized in situ to incorporate fluorescent reporters, allow selective protein recognition, and can be applied to the immobilization of nonadherent cells at the bilayer interface.

SUBMITTER: Perez L

PROVIDER: S-EPMC4706080 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Cell and Protein Recognition at a Supported Bilayer Interface via In Situ Cavitand-Mediated Functional Polymer Growth.

Perez Lizeth L Ghang Yoo-Jin YJ Williams Preston B PB Wang Yinsheng Y Cheng Quan Q Hooley Richard J RJ

Langmuir : the ACS journal of surfaces and colloids 20151006 41

Water-soluble deep cavitands embedded in a supported lipid bilayer are capable of anchoring ATRP initiator molecules for the in situ synthesis of primary amine-containing polymethacrylate patches at the water:membrane interface. These polymers can be derivatized in situ to incorporate fluorescent reporters, allow selective protein recognition, and can be applied to the immobilization of nonadherent cells at the bilayer interface. ...[more]

PMID: 26436343

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