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Aggressive cutaneous zygomycosis caused by Apophysomyces variabilis in an immunocompetent child.

ABSTRACT: A zygomycetous fungus was observed in a biopsy of a 9-year-old male. The patient was presented with severe cutaneous lesions subsequent to a traumatic car accident. Following fungal detection, antifungal treatment was prescribed but condition deteriorated rapidly and above knee amputation was done as lifesaving and to control fungal infection. Analysis of the 28 S rRNA gene (accession KT149770) aligned the isolate with members of the genus Apophysomyces and the pathogen was identified as Apophysomces variabilis.

SUBMITTER: Al-Zaydani IA 

PROVIDER: S-EPMC4706566 | biostudies-literature | 2015 Dec

REPOSITORIES: biostudies-literature

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Aggressive cutaneous zygomycosis caused by Apophysomyces variabilis in an immunocompetent child.

Al-Zaydani Ibrahim A IA   Al-Hakami Ahmed M AM   Joseph Martin R P MR   Kassem Walid M WM   Almaghrabi Mohamed K MK   Nageeb Abdalla A   Hamid Mohamed E ME  

Medical mycology case reports 20151213

A zygomycetous fungus was observed in a biopsy of a 9-year-old male. The patient was presented with severe cutaneous lesions subsequent to a traumatic car accident. Following fungal detection, antifungal treatment was prescribed but condition deteriorated rapidly and above knee amputation was done as lifesaving and to control fungal infection. Analysis of the 28 S rRNA gene (accession KT149770) aligned the isolate with members of the genus Apophysomyces and the pathogen was identified as Apophys  ...[more]

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