Unknown

Dataset Information

0

Optimization of Gentisides Extraction from Gentiana rigescens Franch. ex Hemsl. by Response Surface Methodology.

ABSTRACT: Gentisides are a class of chemical compounds which is considered as potential therapeutic substance for treatment of neurodegenerative disorders. The heat reflux extraction conditions were optimized for seven kinds of gentisides from the root and rhizome of Gentiana rigescens Franch. ex Hemsl. by employing response surface method. Based on univariate test, a Box-Behnken design (BBD) was applied to the survey of relationships between response value (gentisides yield) and independent variables which were chosen from various extraction processes, including extraction temperature, extraction time, and solvent-material ratio. The optimized conditions for this extraction are as follows: extraction time of 3.40?h, extraction temperature of 74.33°C, and ratio of solvent to raw material of 10.21?:?1?mL/g. Verification assay revealed that the predicted value (99.24%) of extraction parameters from this model was mainly conformed to the experimentally observed values (98.61 ± 0.61).

SUBMITTER: Chu B 

PROVIDER: S-EPMC4707016 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Optimization of Gentisides Extraction from Gentiana rigescens Franch. ex Hemsl. by Response Surface Methodology.

Chu Bowen B   Shi Yao Y   Li Zhimin Z   Tian Hao H   Li Wanyi W   Wang Yuanzhong Y  

Journal of analytical methods in chemistry 20151224

Gentisides are a class of chemical compounds which is considered as potential therapeutic substance for treatment of neurodegenerative disorders. The heat reflux extraction conditions were optimized for seven kinds of gentisides from the root and rhizome of Gentiana rigescens Franch. ex Hemsl. by employing response surface method. Based on univariate test, a Box-Behnken design (BBD) was applied to the survey of relationships between response value (gentisides yield) and independent variables whi  ...[more]

Similar Datasets

Genomics Gentiana rigescens Franch. ex Hemsl.
| PRJNA1040803 | ENA
Unknown Amarogentin from <i>Gentiana rigescens</i> Franch Exhibits Antiaging and Neuroprotective Effects through Antioxidative Stress.
| S-EPMC7421772 | biostudies-literature
Unknown Optimization of Phlorizin Extraction from Annurca Apple Tree Leaves Using Response Surface Methodology
| S-EPMC9598179 | biostudies-literature
Unknown The Insulin Receptor: A Potential Target of Amarogentin Isolated from Gentiana rigescens Franch That Induces Neurogenesis in PC12 Cells.
| S-EPMC8160887 | biostudies-literature
Unknown Datasets on the optimization of alginate extraction from sargassum biomass using response surface methodology.
| S-EPMC7327816 | biostudies-literature
Unknown Gentiopicroside, a Secoiridoid Glycoside from <i>Gentiana rigescens</i> Franch, Extends the Lifespan of Yeast via Inducing Mitophagy and Antioxidative Stress.
| S-EPMC7421792 | biostudies-literature
Unknown Optimization of Porphyran Extraction from Pyropia yezoensis by Response Surface Methodology and Its Lipid-Lowering Effects.
| S-EPMC7911723 | biostudies-literature
Unknown Microwave-Assisted Extraction of Cannabinoids in Hemp Nut Using Response Surface Methodology: Optimization and Comparative Study.
| S-EPMC6150297 | biostudies-literature
Unknown Quantitative and Qualitative Characterization of <i>Gentiana rigescens</i> Franch (Gentianaceae) on Different Parts and Cultivations Years by HPLC and FTIR Spectroscopy.
| S-EPMC5471563 | biostudies-literature
Unknown Response Surface Methodology for the Optimization of Flavan-3-ols Extraction from Avocado By-Products via Sonotrode Ultrasound-Assisted Extraction.
| S-EPMC10376872 | biostudies-literature