Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress.
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ABSTRACT:
SUBMITTER: Jadeja RN
PROVIDER: S-EPMC4707288 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
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Data regarding M1 muscarinic receptor-mediated modulation of hepatic catalase activity in response to oxidative stress.
Jadeja Ravirajsinh N RN Urrunaga Nathalie H NH Ahmad Daniel D Khurana Sandeep S
Data in brief 20151218
We recently demonstrated the role of M1 muscarinic receptors (M1R) in modulating oxidative stress in liver and hepatocytes (Urrunaga et al., 2015) [1]. Here we provide data regarding the effect of a novel M1R agonist, VU0357017 (Lebois et al., 2010) [2], on H2O2-mediated hepatocyte injury, the effect of an M1R antagonist VU0255035 (Sheffler et al., 2009) [3] on catalase and super oxide dismutase (SOD) activities in H2O2-treated hepatocytes in vitro, and finally, the effect of M1R ablation on hep ...[more]
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