Monitoring the Effects and Antidotes of the Non-vitamin K Oral Anticoagulants.
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SUBMITTER: Rahmat NA
PROVIDER: S-EPMC4711499 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
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Monitoring the Effects and Antidotes of the Non-vitamin K Oral Anticoagulants.
Rahmat Nur A NA Lip Gregory Y H GY
Arrhythmia & electrophysiology review 20150801 2
In the last decade, we have witnessed the emergence of the oral non-vitamin K oral anticoagulants (NOACs), which have numerous advantages compared with the vitamin K antagonists, particularly their lack of need for monitoring; as a result their use is increasing. Nonetheless, the NOACs face two major challenges: the need for reliable laboratory assays to assess their anticoagulation effect, and the lack of approved antidotes to reverse their action. This article provides an overview of monitorin ...[more]
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