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ABSTRACT:
SUBMITTER: Pande K
PROVIDER: S-EPMC4711633 | biostudies-literature | 2015 Mar
REPOSITORIES: biostudies-literature
Pande K K Schmidt M M Schwander P P Saldin D K DK
Structural dynamics (Melville, N.Y.) 20150301 2
Determination of fast structural changes of biomolecules is usually performed on crystalline samples in a time-resolved pump-probe experiment. Changes in the structure are found by the difference Fourier method using phases of a known reference structure. As we showed recently, such changes can also be determined from diffraction of uncrystallized molecules in random orientations. In this case, the difference in the angular correlations of the diffraction patterns is used to find structural chan ...[more]