Zwitterionic Amphiphilic Homopolymer Assemblies.
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ABSTRACT: Zwitterionic amphiphilic homopolymers can be conveniently prepared in one-pot using activated ester-based polymer precursors. We show that these zwitterionic polymers can (i) spontaneously self-assemble to form micelle-like and inverse micelle-like assemblies depending on the solvent environment; (ii) act as hydrophilic and hydrophobic nanocontainers in apolar and polar solvents respectively; (iii) undergo pH-responsive surface charge and size variations; (iv) exhibit least cytotoxicity compared to structurally analogous amphiphilic homopolymers.
SUBMITTER: Ramireddy RR
PROVIDER: S-EPMC4713042 | biostudies-literature | 2015 Sep
REPOSITORIES: biostudies-literature
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