Unknown

Dataset Information

0

Catalytic self-assembly of a DNA dendritic complex for efficient gene silencing.


ABSTRACT: A catalytic self-assembled DNA dendritic complex was herein reported and used for siRNA-based gene silencing. This kind of one-pot DNA dendrimer can be conveniently prepared as needed, and it was demonstrated to have better silencing efficiency and lower cytotoxicity than commercial cationic lipid transfection agents.

SUBMITTER: Lv Y 

PROVIDER: S-EPMC4713312 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature

altmetric image

Publications

Catalytic self-assembly of a DNA dendritic complex for efficient gene silencing.

Lv Yifan Y   Peng Ruizi R   Zhou Yu Y   Zhang Xiaobing X   Tan Weihong W  

Chemical communications (Cambridge, England) 20160101 7


A catalytic self-assembled DNA dendritic complex was herein reported and used for siRNA-based gene silencing. This kind of one-pot DNA dendrimer can be conveniently prepared as needed, and it was demonstrated to have better silencing efficiency and lower cytotoxicity than commercial cationic lipid transfection agents. ...[more]

Similar Datasets

| S-EPMC5724382 | biostudies-literature
| S-EPMC1868394 | biostudies-literature
| S-EPMC4918363 | biostudies-literature
| S-EPMC2504817 | biostudies-literature
| S-EPMC6774715 | biostudies-literature
| S-EPMC4728372 | biostudies-literature
| S-EPMC4215988 | biostudies-literature
| S-EPMC6390487 | biostudies-literature
| S-EPMC11345760 | biostudies-literature
| S-EPMC4288158 | biostudies-literature