Ontology highlight
ABSTRACT:
SUBMITTER: Niederholtmeyer H
PROVIDER: S-EPMC4714972 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Niederholtmeyer Henrike H Sun Zachary Z ZZ Hori Yutaka Y Yeung Enoch E Verpoorte Amanda A Murray Richard M RM Maerkl Sebastian J SJ
eLife 20151005
While complex dynamic biological networks control gene expression in all living organisms, the forward engineering of comparable synthetic networks remains challenging. The current paradigm of characterizing synthetic networks in cells results in lengthy design-build-test cycles, minimal data collection, and poor quantitative characterization. Cell-free systems are appealing alternative environments, but it remains questionable whether biological networks behave similarly in cell-free systems an ...[more]