Ontology highlight
ABSTRACT:
SUBMITTER: Rotroff DM
PROVIDER: S-EPMC4716583 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Rotroff D M DM Shahin M H MH Gurley S B SB Zhu H H Motsinger-Reif A A Meisner M M Beitelshees A L AL Fiehn O O Johnson J A JA Elbadawi-Sidhu M M Frye R F RF Gong Y Y Weng L L Cooper-DeHoff R M RM Kaddurah-Daouk R R
CPT: pharmacometrics & systems pharmacology 20151029 11
Achieving hypertension (HTN) control and mitigating the adverse health effects associated with HTN continues to be a global challenge. Some individuals respond poorly to current HTN therapies, and mechanisms for response variation remain poorly understood. We used a nontargeted metabolomics approach (gas chromatography time-of-flight/mass spectrometry gas chromatography time-of-flight/mass spectrometry) measuring 489 metabolites to characterize metabolite signatures associated with treatment res ...[more]