Ontology highlight
ABSTRACT:
SUBMITTER: Nowicka U
PROVIDER: S-EPMC4718776 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Nowicka Urszula U Hoffman Morgan M Randles Leah L Shi Xiaoshan X Khavrutskii Lyuba L Stefanisko Karen K Tarasova Nadya I NI Darwin K Heran KH Walters Kylie J KJ
Proteins 20151229 2
Multiple genes in Mycobacterium tuberculosis (Mtb) are regulated by copper including socAB (small orf induced by copper A and B), which is induced by copper and repressed by RicR (regulated in copper repressor). socA and socB encode hypothetical proteins of 61 and 54 amino acids, respectively. Here, we use biophysical and computational methods to evaluate the SocB structure. We find that SocB lacks evidence for secondary structure, with no thermal cooperative unfolding event, according to circul ...[more]