Ontology highlight
ABSTRACT:
SUBMITTER: Carrillo RA
PROVIDER: S-EPMC4720259 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Cell 20151201 7
We have defined a network of interacting Drosophila cell surface proteins in which a 21-member IgSF subfamily, the Dprs, binds to a nine-member subfamily, the DIPs. The structural basis of the Dpr-DIP interaction code appears to be dictated by shape complementarity within the Dpr-DIP binding interface. Each of the six dpr and DIP genes examined here is expressed by a unique subset of larval and pupal neurons. In the neuromuscular system, interactions between Dpr11 and DIP-γ affect presynaptic te ...[more]