Ontology highlight
ABSTRACT:
SUBMITTER: Guptill JT
PROVIDER: S-EPMC4720661 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Guptill Jeffrey T JT Soni Madhu M Meriggioli Matthew N MN
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20160101 1
Myasthenia gravis (MG) is an autoimmune disease associated with the production of autoantibodies against 1) the skeletal muscle acetylcholine receptor; 2) muscle-specific kinase, a receptor tyrosine kinase critical for the maintenance of neuromuscular synapses; 3) low-density lipoprotein receptor-related protein 4, an important molecular binding partner for muscle-specific kinase; and 4) other muscle endplate proteins. In addition to the profile of autoantibodies, MG may be classified according ...[more]