Treatment of inflammatory myopathy: emerging therapies and therapeutic targets.
Ontology highlight
ABSTRACT:
SUBMITTER: Moghadam-Kia S
PROVIDER: S-EPMC4864492 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Publications
Treatment of inflammatory myopathy: emerging therapies and therapeutic targets.
Moghadam-Kia Siamak S Aggarwal Rohit R Oddis Chester V CV
Expert review of clinical immunology 20150827 11
Despite the lack of placebo-controlled trials, glucocorticoids are considered the mainstay of initial treatment for idiopathic inflammatory myopathy and myositis-associated interstitial lung disease. Glucocorticoid-sparing agents are often given concomitantly with other immunosuppressive agents, particularly in patients with moderate or severe disease. First-line conventional immunosuppressive drugs include either methotrexate or azathioprine, and when they fail, more aggressive therapy includes ...[more]
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