Microsatellite instability of gastric cancer and precancerous lesions.
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ABSTRACT:
SUBMITTER: Li B
PROVIDER: S-EPMC4723891 | biostudies-literature | 2015
REPOSITORIES: biostudies-literature
Publications
Microsatellite instability of gastric cancer and precancerous lesions.
Li Bing B Liu Hong-Yi HY Guo Shao-Hua SH Sun Peng P Gong Fang-Ming FM Jia Bao-Qing BQ
International journal of clinical and experimental medicine 20151115 11
<h4>Objective</h4>To investigate whether microsatellite instability (MSI) of gastric cancer and precancerous lesions were existed and its effect.<h4>Methods</h4>Laser microdissection was used. Gastric, intestinal metaplasia, dysplasia and normal mucosa were collected respectively. Five microsatellite loci were selected and MSI was detected by denaturing high-performance liquid chromatography.<h4>Results</h4>In the five microsatellite loci REF-positive phenotype, intestinal metaplasia MSI was 20. ...[more]
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